GREETING
We belong to chemical department in a medical school, and take advantage of such unique environment in our researches. We design and prepare new products based on organic and synthetic chemistry, utilize life science and basic medical science in their functional evaluation using cells and animals, and finally establish technologies useful for researches, disease prevention and therapy.
NEWS
Assoc. Prof. Takemoto received Materials and Devices Joint Research Award 2025.
Mr. Naka (D1) was selected for Kyoto Prefectural University of Medicine Medical Innovation Fellowship.
An article, Plasmid DNA delivery using arginine-rich cell-penetrating L/D-peptides containing α-aminoisobutyric acids., was published in Org.Biomol.Chem.
Mr. Naka received Best Student Presentation Award at the 145th Annual Meeting of the Pharmaceutical Society of Japan (Fukuoka).
An article, Rearrangement in Diamine-Based Polyzwitterion Side Chains for the Modulated pH Responsiveness Regardless of Their Comparable pKa Values, was published in Macromolecular Rapid Communications.
Ms. Danno (D1 student) and Mr. Nakashoya (D1 student) joined our laboratory.
An article, Redox-Responsive Side Chain Structural Changes in a Seven-Membered Cyclic α,α-Disubstituted α-Amino Acid with a Disulfide Bond Enable Reversible Conformational Changes in Peptides, was published in ChemPlusChem (Selected as a front cover).
Prof. Oba will receive The Pharmaceutical Society of Japan Award for Divisional Scientific Promotion.
An article, Visualization of the Plasmid DNA Delivery System by Complementary Fluorescence Labeling of Arginine-Rich Peptides, was published in Chemical and Pharmaceutical Bulletin (Highlighted Paper selected by Editor-in-Chief. Selected by Featured Article. Selected as a front cover.).
An article, Intracellular delivery of plasmid DNA using amphipathic helical cell-penetrating peptides containing dipropylglycine, was published in Chemical and Pharmaceutical Bulletin (Highlighted Paper selected by Editor-in-Chief. Selected by Featured Article.).
Mr. Fukuda (D1 student) and Ms. Shinya (M1 student) joined our laboratory.
An article, Poly(ethylene Glycol) (PEG)–oligoRNA hybridization to mRNA enables fine-tuned polyplex PEGylation for spleen-targeted mRNA delivery, was published in Small Science.
A paper published in ACS Biomater. Sci. Eng. was selected as a Supplementary Cover.
An article, Oligosarcosine conjugation of arginine-rich peptide improves the intracellular delivery of peptide/pDNA complexes, was published in ACS Biomaterials Science & Engineering.
Dr. Umeno received The Pharmaceutical Society of Japan Kanto Branch Award for Young Scientists.
Dr. Umeno joined our laboratory.
An article, Effect of helicity and hydrophobicity on cell-penetrating ability of arginine-rich peptides, was published in Bioorganic & Medicinal Chemistry.
Dr. Takemoto (Associate Professor), Ms. Takayama (research assistant), and Mr. Naka (M1 student) joined our laboratory.